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Why is primase needed for DNA replication?

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Why is primase needed for DNA replication?

Why is primase needed for DNA replication? Primase is the enzyme that synthesizes RNA primers, oligonucleotides that are complementarily bound to a nucleic acid polymer. Primase is required because DNA polymerases cannot initiate polymer synthesis on single-stranded DNA templates; they can only elongate from the 3′-hydroxyl of a primer.

3.5K viewsFeb 5, 2023

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