Chymotrypsin - SlideServe
Chymotrypsin - SlideServe
Jun 11, 2012
slideserve.com
Part 2: Enzymatic Catalysis in Biological SystemsEnzymes can catalyze organic reactions.For example, chymotrypsin is an enzyme that helps digest proteins by cleaving the amide bondnext to aromatic side chains such as phenylalanine.• Draw the mechanism for the hydrolysis of this amide bond of a protein in a food.Chymotrypsin ReactionWhere does the amide bond appear on "the thermodynamic hill"?Low (weak E‡) Medium E‡ High (strong E‡)How strong of a nucleophile is water?Low Medium HighWill this rea
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