Aug 23, 2022 · Factor V Leiden (FAK-tur five LIDE-n) is a mutation of one of the clotting factors in the blood. This mutation can increase your chance of developing abnormal blood clots, most …

“Coagulation factor V” is the name of a protein that helps your blood clot when needed, like after an injury. Your F5 gene tells your body how to make this protein. Most people are born with …

Factor V Leiden is a specific genetic mutation that affects the clotting system in the body. Normally, when a blood vessel is damaged, the clotting system activates to form a blood clot, …

Oct 13, 2024 · Factor V (factor 5) is one of several special proteins in your blood that help it clot. They're called clotting factors. Once the bleeding stops, other proteins tell your clotting...

Factor V Leiden (rs6025 or F5 p.R506Q[1]) is a variant (mutated form) of human factor V (one of several substances that helps blood clot), which causes an increase in blood clotting …

The F5 gene provides instructions for making a protein called coagulation factor V. This protein plays a critical role in the coagulation system, which is a series of chemical reactions that …

Dec 31, 2025 · The factor V Leiden protein is harder to “turn off” than the normal factor V protein. This makes blood clots more likely to form, a condition called thrombophilia.

Aug 15, 2025 · Learn about Factor V Leiden, a genetic mutation that increases the risk of blood clots and venous thromboembolism (VTE).

May 14, 1999 · Factor V Leiden variant refers to missense variant c.1601G>A in F5, which encodes coagulation factor V, a key regulator in the coagulation cascade. Once activated, …

Dec 13, 2011 · A mutation in the factor V gene (F5) increases the risk of developing factor V Leiden thrombophilia. The protein made by F5 called factor V plays a critical role in the …