RMD Open

Spatial gene expression of salivary glands in Sjögren’s disease highlights T follicular helper cell signalling as an indicator of disease pathogenesis

Introduction Sjögren’s disease (SjD) is a systemic, rheumatic autoimmune disorder evidenced by broad organ-specific ...
eLife

The DBD-α4 helix of EWSR1::FLI1 is required for GGAA microsatellite binding that underlies genome regulation in Ewing sarcoma

A discrete helix in the fusion oncoprotein DNA binding domain shifts binding preferences toward long and dense GGAA repeats, which promotes transcriptional hub formation and drives ...
C&EN

A Gene Expression Biomarker Identifies Chemical Modulators of Estrogen Receptor α in an MCF-7 Microarray Compendium

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...
Nature

Aberrant expression of long non-coding RNAs and their regulatory role in chromatin-mediated gene expression changes in the prefrontal cortex of major depressive disorder subjects

Long non-coding RNAs (lncRNAs) have emerged as critical regulators of gene expression, particularly in complex neuropsychiatric disorders such as major depressive disorder (MDD). This study ...
LinkedIn

Microarray Instruments And Reagents in the Real World: 5 Uses You'll Actually See (2025)

Microarray technology has become a cornerstone in modern biological research and clinical diagnostics. It allows scientists and healthcare professionals to analyze thousands of genes simultaneously, ...
Scientific Research Publishing

Squassina, A., Manchia, M., Congiu, D., Chillotti, C., Ardau, R. and Del Zompo, M. (2011) The Use of Gene Expression Microarrays and Whole Exome Sequencing in Lithium ...

ABSTRACT: Lithium has long been established as a first-line mood stabilizer in the treatment of bipolar disorder and treatment-resistant depression. In addition to its psychiatric applications, ...
ascopubs.org

Use of gene expression patterns to identify unique molecular subtypes in muscle invasive bladder cancer: GUSTO.

INSIGHT-005: A new stratum of the explorative, open-labeled, phase I INSIGHT study to evaluate the feasibility and safety, as well as preliminary efficacy, of subcutaneous injections with IMP321 ...
LinkedIn

Hybridization in DNA Microarrays

DNA microarray technology, also known as gene chips or DNA chips, has revolutionized genomics research by enabling hybridization, a process that probes genetic information encoded in DNA. This article ...
IEEE

Microarray Gene Expression Data Classification via Wilcoxon Sign Rank Sum and Novel Grey Wolf Optimized Ensemble Learning Models

Abstract: Cancer is a deadly disease that affects the lives of people all over the world. Finding a few genes relevant to a single cancer disease can lead to effective treatments. The difficulty with ...
BioSpace

Theratechnologies Reports Data Showing High Expression of Sortilin (SORT1) in Multiple Solid Tumors from Tissue Microarrays

Theratechnologies Inc. study demonstrating high expression of sortilin 1 (SORT1) in several solid tumors when compared to normal tissues, to be presented as a poster at the 34th European Organisation ...
IEEE

Application of Bioinformatics in the Design of Gene Expression Microarrays

Abstract: The declaration that gene expression microarrays serve as invaluable tools for the global characterisation of entire genomes is widely accepted by the scientific community highly involved in ...
Frontiers

Integrated Analysis of Expression Profile and Potential Pathogenic Mechanism of Temporal Lobe Epilepsy With Hippocampal Sclerosis

Brain tissues of six patients with TLE+HS and nine of normal temporal or parietal cortices (NTP) of patients undergoing internal decompression for traumatic brain injury (TBI) were collected. The ...