Until now, it has been difficult to maintain retinal ganglion cells deep inside organoids over extended periods. The supply ...

Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...

The Secret Language of Plant Stress Signals When plants face stress, they activate a signaling cascade involving multiple ...

A new study by Scripps Research reveals that alcohol dependence disrupts two signaling pathways in a stress-related part of the brain—and offers insights on developing drugs to treat this condition.

Combined androgen blockade shows significant survival benefits over single-agent ADT in high-risk prostate cancer, as demonstrated by the PRESTO, EMBARK, and ENZARAD trials. The PRESTO trial ...

1 Key Laboratory of Biology and Genetic Improvement of Oil Crops, Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Ministry of Agriculture and Rural Affairs, Wuhan, China ...

Wnt signaling pathways have many important roles in cells and are highly conserved across the animal kingdom from fruit flies to humans. In addition to Wnt signaling being involved in many processes ...

The central image depicts currently used strategies for clinical targeting of TGF-β. Below are methods applicable from preclinical screening to clinical practice, including using humanized mouse ...

Brassinosteroids (BRs) regulate a wide range of developmental and physiological processes in plants through a receptor-kinase signaling pathway that controls the BZR transcription factors Here, we use ...

Hydrogen peroxide (H2O2) is an important signaling molecule in plant developmental processes and stress responses. However, whether H2O2-mediated signaling crosstalks with plant hormone signaling is ...