Chemotherapy drugs that target cancer cells without damaging normal cells remain one of the key goals of precision medicine ...
Researchers at the Icahn School of Medicine at Mount Sinai have developed a first-of-its-kind mRNA system that switches on therapeutic genes preferentially inside targeted cells—an advance ...
RNA is usually portrayed as a molecule that works deep inside the cell, helping to turn genetic information into proteins.
In multiple myeloma, plasma cells proliferate uncontrollably in the bone marrow, disrupting the growth of healthy ...
SMRTS, a smart mRNA system, enables cell‑selective gene expression, expanding the mRNA toolbox for precision cancer therapies.
HIV infects immune cells and establishes long-lasting infections that can progress to acquired immunodeficiency syndrome (AIDS) if left untreated. With the advancement of antiviral therapy (ART), HIV ...
Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers report. The aptamers -- short ...
Balancing the immune system is a delicate act. If it’s too weak, infections and cancer can take hold; if it’s too strong, autoimmune diseases or transplant rejection can occur. Researchers have ...
In a potentially major breakthrough for regenerative medicine, scientists at MIT have developed a way to convert skin cells directly into brain cells extremely efficiently, without needing to go ...