Patients with Omenn syndrome have only a small number of T cells that escape thymic selection, infiltrate peripheral tissues, and cause autoimmune reactions. The origin of the autoreactive T cells ...
We retrospectively analyzed the outcome of hematopoietic stem cell transplantations (HSCT) performed at our Center between 1991 and 2002 in 11 unselected patients with Omenn syndrome, a variant of ...
The fact that two individuals recovered following stem cell transplantation highlights how crucial early detection and treatment are. (Image Credits: Pixabay) A team of researchers at Newcastle ...
At an event dedicating the Omenn-Darling Bioengineering Institute, Princeton University emphasized its commitment to innovative research in the life sciences and engineering, informed by collaboration ...
You have full access to this article via your institution. Despite treatment, pulmonary disease finally worsened requiring ventilation. The child died of systemic multiorgan failure 29 months after ...
Omenn syndrome is a rare, inherited, and often-fatal immune disease associated with defective T and B cell development. It is caused by mutations in recombinase activating genes RAG1 or RAG2, which ...
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