The No. 10 BYU Cougars (7-0, 4-0 Big 12) visit the Iowa State Cyclones (5-2, 2-2) Saturday. Kickoff from Jack Trice Stadium in Ames, Iowa, is at 3:30 p.m. ET (FOX). Let's analyze BetMGM Sportsbook's NCAA football odds around the BYU vs. Iowa State odds and make our expert college football picks and predictions for the best bets.

The undefeated BYU Cougars play at Iowa State on Saturday afternoon. BYU is 7-0 overall, 4-0 in the Big 12. They played rival Utah Utes last week in Provo, winning by a final score of 24-21. Iowa State has a 5-2 record and are 2-2 in conference play.

Iowa State star defensive tackle Domonique Orange will return from ankle injury absence for Week 9 college football matchup with BYU

JACK TRICE STADIUM IOWA STATE HASN’T PLAYED A HOME GAME IN ALMOST A MONTH. THE PLAYERS ARE ITCHING TO GET OUT HERE. IOWA STATE WENT INTO THE BYE WEEK OFF BACK TO BACK LOSSES. COME BACK HOME TO HOST A SEVEN AND ZERO BYU TEAM ON HOMECOMING.

The BYU Cougars remain one of the few undefeated teams left in college football this season, sitting at 7-0 after an impressive win against Utah in Week 8. Now,

It's Iowa State football vs. BYU in Week 9 of the 2025 college football season. Here are predictions for how the game might go.

Big 12 foes match up when the Iowa State Cyclones (5-2) and the No. 10 BYU Cougars (7-0) play on Saturday, October 25, 2025 at Jack Trice Stadium. In their most recent outing, the Cyclones lost 24-17 to the Colorado Buffaloes. The Cougars' last game was a 24-21 win over the Utah Utes.

When the season began, this looked like the hardest game on BYU’s schedule. Don’t let Iowa State's back-to-back losses fool you, it still might be. Iowa State i