Two new research papers from the Living Brain Project at Mount Sinai present what is, by several metrics, the largest ...
RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this ...
This is because it is the RNA, the ribonucleic acid in our bodies, that expresses a gene and controls what the body makes with it. In a paper published in the Journal of Extracellular Vesicles, ...
Recently, demands in RNA manufacturing for long-chain RNAs exceeding 100 nucleotides, such as single guide RNA (sgRNA) for genome editing, have been increasing. Generally, these types of RNA are ...
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The Ultimate Guide to Transcriptomics in Agriculture Using Template Switching
However, traditional protocols that rely on Moloney murine leukemia virus (MMLV) reverse transcriptases (RTs) often fall ...
In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...
SANTA CRUZ — A Ph.D. graduate student in biomolecular engineering at UC Santa Cruz, with a background in computer science and mathematics, has created an innovative software program called CRISPRware, ...
CRISPR-Cas systems are adaptive immune systems found in prokaryotes that defend against invading nucleic acids through CRISPR RNA-guided cleavage. Type V CRISPR-Cas (Cas12) systems, in particular, ...
Peking University, June 27, 2025: To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University ...
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