Gene syntax alters DNA supercoiling to amplify or suppress nearby genes. This could improve the effectiveness of gene ...

The enzyme RNA polymerase (RNAP) carries out transcription, copying DNA into RNA. It's the first step in gene expression, and ...

RNA Polymerase (shown in blue) moves across a template strand of DNA (shown in purple) and transcribes it into RNA (shown in red). But DNA damage blocks the RNA polymerase, causing it to stall and ...

Researchers have uncovered a previously hidden layer of complexity in how genes are activated, showing that water molecules ...

When the molecular machinery in our cells gets to work transcribing the genetic information encoded in DNA into messenger RNA (mRNA), it pauses shortly after starting. Known as promoter-proximal ...

EM, researchers showed that water mediates catalysis and important protein interactions for RNA polymerase II function in ...

Every living cell must interpret its genetic code - a sequence of chemical letters that governs countless cellular functions. A new study by researchers from the Center for Theoretical Biological ...

Thanks to a first-of-its-kind platform, we are starting to understand how the molecular engine responsible for transcription in mammals controls its speed. A team of researchers from The Rockefeller ...

Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as RF-SIRF, that ...