Prostate cancer (PCa) is a highly prevalent malignancy, heavily characterized by complex cellular heterogeneity and highly ...

Researchers have developed Fullscope-seq, a long-read spatial transcriptomics platform that maps alternative transcript isoforms within intact tissues at single-cell resolution - opening new ...

Researchers at the Department of Women's and Children's Health have used a novel technique to map which genes are active in ...

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context. In musculoskeletal ...

This illustration summarizes how integrated spatial transcriptomics, single-cell transcriptomics, single-cell epigenomics, and spatial epigenomics enable multi-dimensional profiling of the tumor ...

Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located. However, the rapid growth of the technology has come at the cost of ...

A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine approaches to treat organ rejection.

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Tissue preparation is the step in spatial transcriptomics that determines whether an experiment succeeds or fails, often before the sample ever reaches the instrument. Getting fixation, sectioning, ...

Spatial transcriptomics now spans two fundamentally different measurement strategies, and the choice between them shapes every downstream result a lab will generate. Sequencing-based platforms capture ...