The San Francisco 49ers and Seattle Seahawks will meet on Saturday at Lumen Field. Here's who experts think will win the divisional-round game.

Welcome to SB Nation Reacts, a survey of fans across the NFL. Each week we ask questions of the most plugged-in Seattle Seahawks fans and fans across the country.

Our 49ers vs. Seahawks picks, odds & expert predictions expect San Francisco's defense to force Sam Darnold to make throws under the bright lights on Saturday, January 17.

Seattle rode its defense to a win over San Francisco to claim the NFC West and the No. 1 seed in the NFC playoffs

Pearsall, Jauan Jennings, and Demarcus Robinson are the best wide receiver trio on the roster. The 49ers will be able to get more accomplished with those three on the field. The loss of Kittle stings, so we’ll see how Kyle Shanahan plans to replace an All-Pro tight end.

Trent Williams replaces Austen Pleasants. Shanahan had to devote resources in pass protection to help Pleasants and did not run wide left behind him once. Williams won’t need help, enabling the Niners to send more receivers on routes to scheme targets open, and running left will be essential.

The family of 72-year-old Randy Santiago Cruz says he's defied doctors’ expectations since November, motivated by his love for the Seahawks.

Sam Darnold is expected to play vs. the 49ers despite having an oblique injury. Jason McIntyre asks if Darnold can lead the 49ers to a victory despite his injury.