Figure 2: Electron density maps of the 30S, 50S and 70S ribosomal particles. Although high quality diffracting crystals of the ribosome have been available for a number of years 5,6, the technical ...

The transport of molecules between the nucleus and cytoplasm is a major task in every eukaryotic cell. Nucleocytoplasmic transport occurs through nuclear pore complexes (NPCs), which are enormous ...

Chloroplast ribosomes, which originated from cyanobacteria, comprise a large subunit (50S) and a small subunit (30S) containing ribosomal RNAs (rRNAs) and various ribosomal proteins. Genes for many ...

Having solved the first crystal structure of a eukaryotic ribosome, scientists are now getting a new, more detailed look at the machinery that translates the genetic code into proteins in all living ...

Maturation of the ribosome is a complex operation. Work now shows that the 90S precursor of the small 40S subunit undergoes a 'molting' process, during which it progressively discards its outermost ...

Researchers reveal how cells regenerate protein factories at endoplasmic reticulum. Researchers at LMU and Stanford University reveal how cells regenerate protein factories at endoplasmic reticulum.

In a recent study published in the journal Nature, researchers examined molecular-level differences in ribosomal translational fidelity between humans and bacteria. Protein synthesis by ribosomes ...

Last year, the Nobel Prize in Chemistry heralded work on DNA transcription, a cornerstone process in molecular biology in which a cell synthesizes a messenger RNA (mRNA) version of genomic DNA. For ...

Thomas A. Steitz, Sterling Professor of Molecular Biophysics and Biochemistry at Yale and one of three winners of the 2009 Nobel Prize in Chemistry, died Oct. 9 at his home in Stony Creek after a ...

Defects in ribosome biogenesis, assembly, and function of individual ribosomes are termed ribosomopathies. They are characterized by tissue-specific phenotypic abnormalities that consequently increase ...

Cells endure starvation conditions by rewiring their metabolic pathways. For example, in yeast, ribosomes are known to coat mitochondria. Exactly how this behavior promotes survival has remained ...

Maturation of the ribosome is a complex operation. Work by an Ludwig-Maximilians-Universitaet (LMU) in Munich team now shows that the 90S precursor of the small 40S subunit undergoes a 'molting' ...