New research reveals that triggering a cell’s DNA damage response could be a promising avenue for developing novel treatments against several rare but devastating viruses for which no antiviral ...

In a groundbreaking study, scientists have discovered more than 100 new human viruses in 252 different gut microbes, ...

University of Pittsburgh researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in ...

In a twist on the question, 'Which came first, the chicken or the egg?', scientists have long faced a similar question about how human adenovirus replicates: 'Which comes first, assembly of the viral ...

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to ...

Viruses use the molecular repertoire of the host cell to replicate. Researchers from the Cluster of Excellence ImmunoSensation2 at the University of Bonn, together with Japanese researchers, want to ...

A common hallmark of viral genome replication is a high mutation rate, which can aid in their ability to evade new treatments and acquire resistance to once-effective antiviral medications. Now, a new ...

The vaccinia virus uses its own machinery and not that of the cell it infects to repair ultraviolet radiation-caused damage to its DNA, according to new research. The virus repurposes an enzyme it ...

Using cryo-microscopy, researchers present a high-resolution structure of monkeypox virus DNA polymerase holoenzyme, a complex that plays a key role in the genome replication process of the virus. The ...