Nature

DNA Replication and Checkpoint Control in S Phase

During DNA replication, the unwinding of strands leaves a single strand vulnerable. How does the cell protect these strands from damage? How would you identify the protein that serves as a connector ...
Phys.org

International team discovers key protein that helps cells maintain their identity

A discovery regarding Mrc1 (Mediator of Replication Checkpoint 1)—a fission yeast protein involved in DNA replication—has been published in Cell. The discovery is the result of an international ...
ascopubs.org

Identification of DNA repair/replication genes mutations in determining response to immune checkpoint inhibitors in non-small cell lung cancer patients.

A phase 1 trial of JS001, a monoclonal antibody targeting programmed death-1 (PD-1) in patients with advanced or recurrent malignancies. This is an ASCO Meeting Abstract from the 2017 ASCO Annual ...
EurekAlert!

Replication Checkpoint Identified in Cholera Bacteria

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert ...