RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this ...
MetaGraph compresses vast data archives into a search engine for scientists, opening up new frontiers of biological discovery ...
The company says the system can benefit pharmaceutical and biotech firms seeking rapid feedback on drug candidates or genome editing.
In a major advance for biotechnology and bioinformatics, researchers from ETH Zurich have developed MetaGraph, a search ...
Combined Transcriptome and Circulating Tumor DNA Longitudinal Biomarker Analysis Associates With Clinical Outcomes in Advanced Solid Tumors Treated With Pembrolizumab The prognostic model demonstrated ...
RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...
Discover the biological significance of hidden RNAs and learn how to detect them in RNA-Seq data using advanced techniques.
Mikhail Karasikov and his colleagues at ETH Zurich worked on MetaGraph, a search engine designed for genomic databases ...
An individual’s genome is identifiable. But datasets of RNA sequences from single cells are like a blurry photocopy of the genome. The sequence numbers are small, the data are noisy, and the sequences ...