Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, No. 15 (Jul. 22, 2003), pp. 8692-8697 (6 pages) The DnaA replication initiation protein has been shown to be ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, No. 13 (Jun. 21, 1994), pp. 5962-5966 (5 pages) In a search for trypanosome DNA sequences that permit ...

Toxin-antitoxin (TA) systems are now known to negatively control plasmid replication. Toxin-antitoxin (TA) systems are now known to negatively control plasmid replication, according to Thomas Wood, ...

Plasmid DNA (pDNA) is a fundamental starting material for therapeutic development, including for viral vectors, mRNA therapies, and DNA vaccines. Researchers use capture methods such as anion exchange ...

As cell and gene therapies, mRNA vaccines and other cutting-edge meds come into their own, developers have put a strain on the industry's supply chain. That’s where biopharma building block outfits ...

DNA-based information is a new interdisciplinary field linking information technology and biotechnology. The field hopes to meet the enormous need for long-term data storage by using DNA as an ...

Adeno-associated virus (AAV) vectors play a pivotal role in gene therapy, delivering therapeutic genes with high precision and safety. However, a significant challenge in the biomanufacturing of these ...

Genes responsible for antimicrobial resistance (AMR) can spread from microbe to microbe through circular genetic material called plasmids, and this lateral transfer occurs in the gut. This week in ...