In the developing brain, neurons must navigate through complex and often crowded tissue to reach their final destinations—this process is crucial for proper brain formation and function. Similar to ...
The structure and functions of the tip of migrating neurons remain elusive. A research group has found that the PTPσ-expressing growth cone senses the extracellular matrix and drives neuronal ...
A study shows how newly created neurons depend on blood flow to travel to their final location in the adult brain, paving the way for future research on blood flow-dependent cell migration which may ...
The entorhinal cortex is one of the most interconnected brain regions and is essential for spatial navigation and memory formation 1. These abilities mature throughout childhood, and have generally ...
Researchers from the University of New Hampshire looked at the developmental process of the cerebral cortex—the outermost layer of the brain—and examined how neurons, or nerve cells, refine their ...
The assembly of a healthy brain requires new cells to travel incredibly long distances to arrive at their correct final destinations. A recent laboratory mouse study reveals that dopamine receptors ...
Neuronal precursors from a particular region of the ventral forebrain--the medial ganglionic eminence (MGE)--are capable of migrating extensively in both the embryonic and adult brain and ...
Newborn mice neurons can snap both DNA strands to migrate, then repair the breaks within a day. The process may be a normal ...
Using microfluidic devices mimicking the crowded spaces in the developing brain, researchers gained novel insights into distinct modes of locomotion found in neurons. In the developing brain, neurons ...