Twenty doses of outpatient HD-MTX with glucarpidase were administered to seven patients. After 20 of 20 (100%) treatments, serum MTX levels were reduced to <100 nmol/L. Treatments were well-tolerated, ...

Adalimumab monotherapy and combination with methotrexate showed similar drug survival and PASI75 response rates in plaque psoriasis patients. Methotrexate reduced antidrug antibody levels but did not ...

In July 2022, the US Food and Drug Administration (FDA) expanded the labeling of Krystexxa (pegloticase; Horizon Therapeutics), a PEGylated uric acid-specific enzyme, to include coadministration with ...

Subcutaneous tocilizumab, either as monotherapy or in combination with methotrexate, demonstrated greater efficacy than methotrexate alone and was well tolerated in patients with active rheumatoid ...

Please provide your email address to receive an email when new articles are posted on . Patients who paused methotrexate treatment upon receiving a COVID-19 vaccine booster had significantly greater ...

Systemic therapy for sarcoidosis is reserved for organ-threatening disease, and laryngeal involvement necessitates treatment ...

HealthDay News — Methotrexate and cyclosporine have the lowest monthly cost for treating psoriasis, study findings published in the Journal of the American Association of Dermatology indicate. “Newer ...

Please provide your email address to receive an email when new articles are posted on . Low-dose methotrexate did not relieve pain or reduce synovitis in inflammatory knee OA. The findings do not ...

Methotrexate significantly lowers systolic blood pressure in newly diagnosed RA patients compared to sulfasalazine, potentially reducing cardiovascular risk. The study provides prospective comparative ...