Insulin metabolism encompasses the synthesis of proinsulin in pancreatic β-cells, its processing into mature hormone and C-peptide, and regulated release in response to glucose and incretin signals.

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide. In affected people, insulin is unable to ...

The therapeutic goals for treatment of hyperglycemic crises in diabetes consist of 1) improving circulatory volume and tissue perfusion, 2) decreasing serum glucose and plasma osmolality toward normal ...

In a recent study published in Nutrients, researchers evaluate the short- and long-term effects of sucralose consumption on glucose utilization and blood glucose regulation, respectively, using a ...