Neurons in the brains of Alzheimer’s patients are being destroyed from the inside before the disease’s signature plaques ever ...

A team of researchers from the Institute of Applied Sciences and Intelligent Systems of the National Research Council of Italy (ISASI-CNR) and the Telethon Institute of Genetics and Medicine (TIGEM) ...

The fight against cancer often begins with uncovering hidden players, and a recent study reveals one such key player: an unexpected class of abbreviated N-glycans. These molecules, upregulated in ...

A new study has identified mutations in a single gene as the cause of a previously unrecognized spectrum of severe neurological disorders ranging from fatal prenatal conditions to progressive ...

Azafaros, a private company building a portfolio of disease-modifying therapeutics to become a leader in lysosomal storage disorders (LSDs) focused on addressing neurological symptoms, today announced ...

If you had to swallow a pouch of toxins, you’d like to be certain the pouch was indestructible. Similarly, every eukaryotic cell seeks to ensure that the membranes of its many miniscule sacs called ...

Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes. The breakthrough ...

The duplication and division of cells is critical to keeping all multicellular organisms alive. But the opposite process is equally important: cell death. Controlled death of cells, or programmed cell ...

Stanford researchers constructed an atlas of the proteins found in the lysosome across different brain cell types, a recently published paper reported. Lysosomes are cell organelles that play ...