Humanized immune system (HIS) mice provide researchers with a unique opportunity to study human immune responses in a living organism. Developed to address the lack of suitable in vivo models for ...

Researchers corrected lamin A gene mutations, preventing skeletal and cardiac abnormalities and extending mice lifespans.

In what may be one of the most important HIV research breakthroughs in years, scientists have discovered a strikingly ...

Humanized immune system (HIS) mouse models have become indispensable for advancing translational research in immuno-oncology, autoimmune disorders, and infectious disease. This webinar will begin with ...

Genetically-humanized FcRn mice provide translational pharmacokinetics (PK) and pharmacodynamics (PD) data for antibody-based therapeutics. The image illustrates a therapeutic antibody (blue) adhering ...

Desmoplastic nodular medulloblastoma: A National Cancer Database analysis of patient demographics and survival. A phase 1 study to evaluate the safety and tolerability of BXQ-350, a novel sphingolipid ...

Since the development of the super immunodeficient CIEA NOG mouse® in the early 2000s enabled improved humanized immune system (HIS) mice, HIS models have been widely adopted in immuno-oncology ...

RJVA-002 achieved ~30% weight loss at five weeks in a translational obesity model; weight loss not yet plateauedPreclinical ...