In September 1970, Janet Mertz joined the biochemistry department at Stanford University. She was one of only six new graduate students in the department and the first female one admitted in nine ...

Adeno-associated viruses (AAVs) have emerged in recent years as a crucial tool in clinical gene therapies, offering low pathogenicity and long-lived gene expression in target cells. AAVs are simple ...

Recombinant DNA (rDNA) refers to artificial DNA molecules that are created by combining genetic material from different sources. This technology involves the insertion of DNA fragments from one ...

To establish chronic disease, the hepatitis B virus (HBV) must have its genome of relaxed circular DNA (rcDNA) turned into covalently closed circular DNA (cccDNA). Exactly how rcDNA becomes cccDNA has ...

Gene editing was a new idea in the mid-1970s. So when two of America's most prestigious research institutions planned a new facility for work in recombinant DNA, the technology that lets scientists ...

Scientists from the J. Craig Venter Institute (JCVI), the Friedrich-Loeffler-Institut (FLI), and the International Livestock Research Institute (ILRI) say they have developed a reverse genetics system ...

A huge budget increase proposed by the president. Numerous legislative initiatives at the federal and state level. Public fears of biological harm. That is the new reality brought to us by ...

Proteins are the fundamental building blocks of life, and they are the essential products of molecular biology’s core dogma. Proteins play a variety of roles in the body, including catalyzing ...

In September, David Baltimore — the scientist who discovered reverse transcriptase, a breakthrough often described as one of ...