The question of how denatured proteins fold into their native conformation is still one of the major unsolved problems in biophysical chemistry. Electrospray ionization (ESI) mass spectrometry (MS) is ...

Electrospray ionization mass spectrometry (ESI-MS) has emerged as a pivotal analytical tool, enabling the gentle conversion of analytes in solution into gas-phase ions while minimising fragmentation.

ass spectrometry (MS) has evolved into one of the most sensitive analytical methods for the structural characterization of molecules. 1,2 Ionization is critical for volatilizing sample analytes into a ...

Mass spectrometry (MS) is already perhaps the most popular analytical chemistry tool in drug discovery and development. Its use is ubiquitous in bioanalytical laboratories for drug and metabolite ...

Current drug discovery workflows rely on the synthesis and bioactivity assessment of large compound libraries, both processes which heavily depend on high-throughput (HT) experimentation to be able to ...

Incidence and characteristics of breast cancer following a diagnosis of ductal carcinoma in situ. This is an ASCO Meeting Abstract from the 2013 ASCO Annual Meeting I. This abstract does not include a ...

The life science mass spectrometry industry has experienced a boom recently with a spate of new instruments and technological advances. Billerica, Mass.-based Bruker Daltonics continues this trend ...

Protein-protein interactions are integral to a wide range of biological processes, including hormone, neurotransmitter or drug binding, antigen recognition, and enzyme-substrate interactions.