During mitosis in budding yeast, dynein moves the mitotic spindle into the mother-bud neck. We have proposed an offloading model to explain how dynein works. Dynein is targeted to the dynamic plus end ...

Cytoplasmic dynein is a vital microtubule-based motor protein that drives retrograde intracellular transport, supporting essential cellular functions ranging from organelle positioning to cell ...

Movement signals life, and nowhere is this truer than inside a living cell. The millions of proteins and molecules within each of our cells bend, travel and conform in a complex but orchestrated ...

The most lethal feature of any cancer is metastasis, the spread of cancer cells throughout the body. New research reveals the mechanics behind how breast cancer cells may invade healthy tissues. The ...

Flagella and cilia are critical cellular organelles that provide a means for cells to sense and progress through their environment. The central component of flagella and cilia is the axoneme, which ...

CORVALLIS, Ore. (KTVZ) – Oregon State University scientists say they have taken a key step toward better understanding neurodegenerative diseases by using a suite of biophysical techniques to learn ...

Researchers have uncovered the mechanism by which a protein facilitates the spread of breast cancer cells from the primary tumor into healthy tissue. The discovery not only improves our understanding ...

A mechanism of dynein-powered metastatic locomotion has been identified using soft tissue models, revealing a new clinical target for breast cancer treatment. New research led by Penn State (PA, USA) ...

Scientists have taken a key step toward better understanding neurodegenerative diseases by using a suite of biophysical techniques to learn more about a motor protein whose malfunction is associated ...

CORVALLIS, Ore. – Oregon State University scientists have taken a key step toward better understanding neurodegenerative diseases by using a suite of biophysical techniques to learn more about a motor ...