One in five patients taking commonly prescribed diuretics for blood pressure or heart conditions end up with reduced sodium and potassium levels, which can lead to a range of health problems. Yet ...

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Diuretic therapy remains a vital cog in the management of hypertension; either as monotherapy or in combination with other antihypertensive classes. However, maximizing the antihypertensive effect of ...

Kidney stones affect nearly 10% of the global population. For more than three decades, thiazide diuretics, a common medication used for high blood pressure, have been the standard of care for kidney ...

Urea transporters (UT) play a vital role in the mechanism of urine concentration and are recognized as novel targets for the development of salt-sparing diuretics. Thus, UT inhibitors are promising ...