Many diseases, including Alzheimer’s and Parkinson’s, are characterized by the formation of clumps of long protein fibrils. Smaller intermediates that form first are suspected by some scientists to be ...
Proteins that make amyloids can bend and twist into a variety of shapes in the process. Two new papers, in the March 9 Science and March 8 PNAS online, describe structures for a cylindrical oligomer ...
An unusual protein structure known as a “rippled beta sheet,” first predicted in 1953, has now been created in the laboratory and characterized in detail using x-ray crystallography. The new findings, ...
The inhibition of pathological protein-protein interactions is a promising approach for treating a large number of diseases, including many forms of cancer. A team of researchers has now developed a ...
An unusual protein structure known as a "rippled beta sheet," first predicted in 1953, has now been created in the laboratory and characterized in detail using x-ray crystallography. The new findings, ...
The inhibition of pathological protein-protein interactions is a promising approach for treating a large number of diseases, including many forms of cancer. A team of researchers has now developed a ...
An unusual protein structure known as a 'rippled beta sheet,' first predicted in 1953, has now been created in the laboratory and characterized in detail using x-ray crystallography. The new findings ...
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