Scientists have shown the efficacy of a new non-opioid oral painkiller known as ADRIANA, the world's first selective α2B-adrenoceptor antagonist – a receptor subtype not previously targeted for ...

The adrenaline receptor studied is a member of the G protein-coupled receptor (GPCR) family, and this family is the target of one-third of all Food and Drug Administration (FDA)-approved drugs.

Experiments in which they then used beta-blockers to block the ARBD1 receptor in chronically infected mice resulted in more-functional killer T cells that were better at destroying cancer cells.

“The promising results presented in this study suggest that dexmedetomidine reduces agitation through potent, selective agonist action at central alpha-2 adrenergic receptors, providing an ...

The cause of dilated cardiomyopathy (DCM) can be associated with the presence of the TTN gene combined with preexisting comorbidities like atrial fibrillation, which increase the odds of developing ...

Gemtesa works directly on the beta-3 adrenergic receptors in the bladder muscle. Receptors are like doors that require a chemical “key” to open them and make reactions happen in the body.

"What our studies suggest is that KLF15 is necessary to keep bad fat cells bad," said Feldman. The reason: KLF15 binds to the beta-adrenergic receptor ADRB1 and switches it off. In experiments ...