Oklahoma vs Ole Miss prediction, pick, odds, spread
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The No. 8 Ole Miss Rebels (6-1) and the No. 13 Oklahoma Sooners (6-1) link up on Saturday afternoon in a critical SEC matchup with both conference and College Football Playoff implications. The Rebels had their six-game win streak halted last weekend in a 43-35 loss at Georgia. Meanwhile, Oklahoma took down South Carolina 26-9.
John Mateer faces Ole Miss in a crucial SEC clash, and our bold predictions reveal how the Sooners QB will handle the pressure.
The Sooners on SI staff offers their predictions for the No. 13-ranked Sooners’ home contest against the No. 8-ranked Ole Miss Rebels.
The SEC's new schedule format pairs Oklahoma with Ole Miss as a permanent opponent, a decision that has surprised many. Fans, media personalities, and even Ole Miss coach Lane Kiffin have expressed confusion over the matchup due to a lack of history or geographical connection.
Joel Klatt broke down the Ole Miss Rebels travelling to Norman to take on the Oklahoma Sooners. He analyzed if Oklahoma could potentially upset Ole Miss. Joel questioned if Oklahoma's offense can compete and if Ole Miss's defense will be stronger this weekend.
Ole Miss' offense is more complete than any of the Sooners' first seven opponents of 2025, and OU's defense will have to be at its best on Saturday.
Sooners wide receiver Keontez Lewis ran headfirst into a brick wall near the field of play three weeks ago and was carted off.
EJ Manuel and Sam Acho explain their concerns with Ole Miss's defense and why the Rebels may have problems against Oklahoma's running game.