Louisville returns home after picking up one of its biggest wins in school history, knocking off No. 2 Miami 24-21 at Hard Rock Stadium on Friday night. It was the school’s seco

College football Week 9 odds, picks, predictions, TV channel, streaming for Boston College Eagles vs Louisville Cardinals ACC game Saturday, Oct. 25.

Boston College vs Louisville betting odds, kickoff, TV, injury report and an actionable pick. Bettor-first breakdown and clear projection.

Louisville's backup running backup Duke Watson, for the second straight week, was designated as "out" on the first injury report after exiting the Virginia game three weeks ago. Starting defensive end Wesley Bailey, as well as rotational offensive lineman Naeer Jackson, were both listed as "questionable."

Pregame analysis and predictions of the Boston College Eagles vs. Louisville Cardinals NCAAF game to be played on October 25, 2025 on ESPN.

Jeff Brohm is 0-5 in games immediately after a top-10 win. Can Louisville, fresh off an upset at Miami, avoid a loss against Boston College?

LOUISVILLE, Ky. - On the heels of capturing one of their biggest road wins in program history, the Louisville program is returning home, where a matchup with Boston College is waiting for them. Kickoff from L&N Stadium is set for Saturday, Oct 25 at 7:30 p.m. EST.